Rat IL-1ß,2205







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	Rat IL-1ß


	Rat IL-b Rat Interleukin-1 beta, (IL-1b) is a ~17 kDa protein composed of 153 amino acids. IL-1 b along with IL-1α, is a member of the IL-1 superfamily. IL-1α and IL-β are pro-inflammatory cytokines involved in immune defense against infection. IL-1 a and IL-1 b, are the products of distinct genes, but recognize the same cell surface receptors. IL-1 a and IL-1 b are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. When stimulated by other cytokine growth factors, mRNA of IL-1β is present within 15 minutes and accumulates for 4 hours followed by a rapid fall that results in part from the synthesis of a transcriptional repressor as well as a decrease in mRNA half-life. IL-1β plays a role in signal transduction through its receptor, IL-1R. IL-1β is a converting enzyme, which plays an important role in apoptosis through nitric oxide.

Rat IL-1bF

The specifications of the Rat IL-1β ELISA Test Kit are as follows:

Format: 96-well strip plate

Assay range: 30-1920 pg/ml

Sensitivity: 15 pg/ml

Total Assay Incubation Time: 3 hour and 45 minutes

Sample Size: 100 µl/well

Sample types: Serum, plasma and Cell Culture Supernatant

Wavelength for plate reading: A450 nm

Product Code	Unit	Price	Availability
2205	30-1920 pg/ml