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HOME > Functional Assays > Membrane Potential
Oxonol VI
   
ÄÚ    µå : 21417
´Ü     À§ : 25 mg
°ø ±Þ ¿ø : ABD Bioquest
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  Oxonol V
Oxonol VI [Bis-(3-propyl-5-oxoisoxazol-4-yl)pentamethine oxonol]


Storage : 4¡É
Ex (nm) / Em (nm) : 599 / 634
Solvent  : DMSO

Molecular Formula   : C17H20N2O4
Molecular Weight     : 316.35
CAS Number/Name : 64724-75-0 / 5(4H)-Isoxazolone, 4-(5-(5-hydroxy-3-propyl-4-isoxazolyl)-2,4-pentadienylidene) -3-propyl-


Oxonol VI is a sensitive slow-response membrane potential probe that has faster response than Oxonol V. The fluorescence of Oxonol VI decreases upon membrane hyperpolarization. In general, slow-response probes exhibit potential-dependent changes in their transmembrane distribution that are accompanied by a fluorescence change. The magnitude of their optical responses is much larger than that of fast-response probes (typically a 1% fluorescence change per mV). Slow-response probes, which include cationic carbocyanines, rhodamines and anionic oxonols, are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.
   
 
  Oxonol

Product Code

Unit

Price

Availability

21417

25 mg