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 HOME > Functional Assays > Calcium Detection |
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Calbryte™ 520 AM |
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코 드 |
: 20651 |
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단 위 |
: 10x50 ug |
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공 급 원 |
: AAT bioquest |
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가 격 |
: 문의 |
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Calbryte 520 AM
Calbryte™ 520 AM
Ex/Em (nm) 492/514
MW 1090.90
CAS # N/A
Solvent DMSO
Storage -15℃, F/D/L
Calbryte™ 520, AM is a new fluorescent and cell-permeable calcium indicator. Like other dye AM cell loading, Calbryte™ 520 AM ester is non-fluorescent and once gets inside cells, it is hydrolyzed by intracellular esterase and gets activated. The activated indicator is a polar molecule that is no longer capable of freely diffusing through cell membrane, essentially trapped inside cells. Upon binding Ca2+ ions, Calbryte™ 520 produces bright fluorescence signal with extremely high signal/background ratio. In addition, Calbryte™ 520 demonstrates greatly improved intracellular retention. It has the identical excitation and emission wavelength as Fluo-4, thus the same Fluo-4 assay settings can be readily applied to Calbryte™ 520-based calcium assays. Calbryte™ 520 is a new generation of fluorescent indicators for the measurement of intracellular calcium. Its greatly improved signal/background ratio and intracellular retention properties make Calbryte™ 520 AM the most robust indicator for evaluating GPCR and calcium channel targets as well as for screening their agonists and antagonists in live cells. |
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>Calbryte 520 AM
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Product Code |
Unit |
Price |
Availability |
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20650 |
2x50 ug
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20651 |
10x50 ug
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20653 |
1 mg |
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20656 |
2x50 ug
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20658 |
10x50 ug
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